Neutralization of hydrochloric acid formed when chlorine gas reacts with water in the airways. Prevents convertion of ferrous to ferric.Ĭardiotoxic drug affecting fast sodium channel (TCA, cocaine)ĭecreases affinity of cardiotoxic drugs to the fast sodium channel. Neutralizes venom by binding with circulating venom components and with locally deposited venom by accumulating at the bite site. Promotes the conversion of toxic metabolite glycolic acid to glycine. Reverses acute pyridoxine deficiency by promoting GABA synthesis. Adjunctive therapy in ethylene glycol poisoning. Isoniazid, theophylline, monomethyl hydrazine. Protamine that is strongly basic combines with acidic heparin forming a stable complex and neutralizes the anticoagulant activity of both drugs. It also has direct, but less marked, positive inotropic and chronotropic effects on cardiac muscle and vasodilator effects on vascular smooth muscle.Ī reversible anticholinesterase which effectively increases the concentration of acetylcholine at the sites of cholinergic transmission.īypasses inhibition of Vitamin K epoxide reductase enzyme. Regitine produces an alpha-adrenergic block of relatively short duration.
#DIAZEPAM ANTIDOTE FREE#
Oxidizes hemoglobin to methemoglobin which binds the free cyanide and can enhance endothelial cyanide detoxification by producing vasodilation.Ĭopper, gold, lead, mercury, zinc, arsenic
Naloxone is believed to antagonize opioid effects by competing for the µ, κ and σ opiate receptor sites in the CNS, with the greatest affinity for the µ receptor.Īnticholinesterase which causes accumulation of acetylcholine at cholinergic receptor sites. Prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Protects the healthy cells from the effects of methotrexate while allowing methotrexate to enter and kill cancer cells.Ī “chemoprotectant” drug that reduces the undesired effects of certain chemotherapy drugs.Ĭhemical producing severe methemoglobinemia. Used in combination with vasodilator phentolamine or nitroprusside to prevent local thrombosis and ischemia.įorms cyanocobalamin, a non-toxic metabolite that is easily excreted through the kidneys. Reverses hypercoagulable state by interacting with antithrombin III. Stimulates the formation of adenyl cyclase causing intracellular increase in cycling AMP and enhanced glycogenolysis and elevated serum glucose concentration.ĭextrose (the monosaccharide glucose) is used, distributed and stored by body tissues and is metabolized to carbon dioxide and water with the release of energy. This enzyme plays a key role in the metabolism of ethylene glycol and methanol.īeta blockers and calcium channel blockers Reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABA A receptor.Ī competitive inhibitor of the enzyme alcohol dehydrogenase found in the liver. Not known partial protection against acute hepatic failure may displace amatoxin from protein-binding sites allowing increased renal excretion may also inhibit penetration of amatoxin to hepatocytes.ĭeferoxamine acts by binding free iron in the bloodstream and enhancing its elimination in the urine.īinds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body.Ĭhelation of lead ions and endogenous metals (e.g., zinc, manganese, iron, copper).Ī potent antagonist to acetylcholine in muscarinic receptors. Interrupts the entero-hepatic cycle with multiple dose.Īlbuterol inhaler, insulin & glucose, NaHCO 3, kayexalateĬompetitive inhibition of muscarinic receptors. Non-specific poisons except cyanide, iron, lithium, caustics and alcohol.Ībsorption of drug in the gastric and intestinal tracts. Restores depleted glutathione stores and protects against renal and hepatic failure.
The following are antidotes that should be familiarized by the nurse to respond to this emergency situation quickly. This post will help you familiarize yourself with the common antidotes that are used in the hospital setting. The term antidote is a Greek word meaning “given against”. An antidote is a substance that can counteract a form of poisoning.
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